Overview of Plant-Derived Vaccine Antigens: Dengue Virus

Authors

  • Ravindra B Malabadi
  • Advaita Ganguly
  • Jaime A Teixeira da Silva
  • Archana Parashar
  • Mavanur R Suresh
  • Hoon Sunwoo

DOI:

https://doi.org/10.18433/J3401K

Abstract

ABSTRACT - This review highlights the advantages and current status of plant-derived vaccine development with special reference to the dengue virus. There are numerous problems involved in dengue vaccine development, and there is no vaccine against all four dengue serotypes. Dengue vaccine development using traditional approaches has not been satisfactory in terms of inducing neutralizing antibodies. Recently, these issues were addressed by showing a very good response to inducing neutralizing antibodies by plant-derived dengue vaccine antigens. This indicates the feasibility of using plant-derived vaccine antigens as a low-cost method to combat dengue and other infectious diseases. The application of new methods and strategies such as dendritic cell targeting in cancer therapy, severe acute respiratory syndrome, tuberculosis, human immune deficiency virus, and malaria might play an important role. These new methods are more efficient than traditional protocols. It is expected that in the near future, plant-derived vaccine antigens or antibodies will play an important role in the control of human infectious diseases. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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Published

2011-10-21

How to Cite

Malabadi, R. B., Ganguly, A., Teixeira da Silva, J. A., Parashar, A., Suresh, M. R., & Sunwoo, H. (2011). Overview of Plant-Derived Vaccine Antigens: Dengue Virus. Journal of Pharmacy & Pharmaceutical Sciences, 14(3), 400–413. https://doi.org/10.18433/J3401K

Issue

Section

Review Articles