An Overview of Tissue Engineering as an Alternative for Toxicity Assessment

Authors

  • Mathew Garrod The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.
  • David Yi San Chau The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.

DOI:

https://doi.org/10.18433/J35P6P

Abstract

Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population. However, parallel to this milestone, is the exploitation of the biomimetic constructs as feasible alternatives to in vivo/ex vivo toxicity testing models due to their accurate representation of innate tissue and organs. Herein, we summarise a range of concepts within tissue engineering with a particular emphasis on biological material selection and implications to animal testing.

 

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Author Biographies

Mathew Garrod, The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.

MPharm, Department of Pharmacy

David Yi San Chau, The Research Centre in Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology and Postgraduate Medicine, School of Life and Medical Sciences, University of Hertfordshire, College Lane, Hatfield, UK.

Senior Lecturer in Pharmaceutics, Department of Pharmacy

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Published

2016-02-04

How to Cite

Garrod, M., & Chau, D. Y. S. (2016). An Overview of Tissue Engineering as an Alternative for Toxicity Assessment. Journal of Pharmacy & Pharmaceutical Sciences, 19(1), 31–71. https://doi.org/10.18433/J35P6P

Issue

Vol. 19 No. 1 (2016)

Section

Review Articles

License

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