Overview of Nanoparticle Coating of Dental Implants for Enhanced Osseointegration and Antimicrobial Purposes

Feridoun Parnia1, Javad Yazdani1, Vahid Javaherzadeh2, Solmaz Maleki Dizaj3

1Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
2Science and Research Branch, Islamic Azad University, Tabriz, Iran.
3Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract


PURPOSE: Nanomaterials are suitable candidates for coating of titanium based (Ti-based) dental implants due to their unique properties. The objective of this article is to summarize the application of nanoparticles as Ti-based implant coating materials in order to control and improve the implant success rate with focus on enhanced osseointegration and antimicrobial purposes. METHOD: This review was conducted using electronic databases and MeSH keywords to detect associated scientific literature published in English. RESULTS: The reviewed articles exhibited that a significant progress in research has occurred in the case of nanomaterial-based coatings for dental implants. Coating of Ti surfaces with nanoparticles can improve soft tissue integration and osteogeneration that leads to improved fixation of implants. Furthermore, osteoconductive nanoparticles induce a chemical bond with bone to attain good biological fixation for implants. Surface modification of implants using antibacterial properties can also decrease the potential for infection, and certainly, present improve clinical outcomes. CONCLUSIONS: Considering the reported success, more clinically and in vivo information on the nanoparticle-based implant coatings will add to the successful application of the device in the clinic.

 

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J Pharm Pharm Sci, 20 (0): 148-160, 2017

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DOI: http://dx.doi.org/10.18433/J3GP6G