Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone

Authors

  • Abolghasem Jouyban Tabriz University of Medical Sciences
  • Mohammad Amin Abolghasemi Fakhree Tabriz University of Medical Sciences
  • Ali Shayanfar Kimia Research Institute

DOI:

https://doi.org/10.18433/J3P306

Abstract

N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.

Downloads

Download data is not yet available.

Downloads

Published

2010-11-15

How to Cite

Jouyban, A., Fakhree, M. A. A., & Shayanfar, A. (2010). Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone. Journal of Pharmacy & Pharmaceutical Sciences, 13(4), 524–535. https://doi.org/10.18433/J3P306

Issue

Vol. 13 No. 4 (2010)

Section

Review Articles

License

This is an open access journal with free of charge non-commercial download. At the time of submission, authors will be asked to transfer the copyright to the accepted article to the Journal of Pharmacy and Pharmaceutical Sciences. The author may purchase the copyright for $500 upon which he/she will have the exclusive copyright to the article. Nevertheless, acceptance of a manuscript for publication in the Journal is with the authors' approval of the terms and conditions of the Creative Commons copyright license Creative Common license (Attribution-ShareAlike) License for non-commercial uses.

CLOCKSS system has permission to collect, preserve, and serve this Archival Unit.