Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone

Authors

  • Abolghasem Jouyban Tabriz University of Medical Sciences
  • Mohammad Amin Abolghasemi Fakhree Tabriz University of Medical Sciences
  • Ali Shayanfar Kimia Research Institute

DOI:

https://doi.org/10.18433/J3P306

Abstract

N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.

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Published

2010-11-15

How to Cite

Jouyban, A., Fakhree, M. A. A., & Shayanfar, A. (2010). Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone. Journal of Pharmacy &Amp; Pharmaceutical Sciences, 13(4), 524–535. https://doi.org/10.18433/J3P306

Issue

Section

Review Articles