Vol 21 (2018)

Pages 305 - 515

Table of Contents

Pharmaceutical Sciences; Original Research Articles

in vitro- and in vivo Evaluation of Methotrexate-Loaded Hydrogel Nanoparticles Intended to Treat Primary CNS Lymphoma via Intranasal Administration
Leila Pourtalebi Jahromi , Soliman Mohammadi-Samani , Reza Heidari , Amir Azadi
PDF
305-317
Icariside II Attenuates Chronic Hydrocephalus in an Experimental Subarachnoid Hemorrhage Rat Model
Ce Dong , Xing Ming , Zhanying Ye , Pengfei Wang , Lin Wang , Zheng Li , Baogen Pan
PDF
318-325
Calcium Signal Pathway is Involved in Prostaglandin E2 Induced Cardiac Fibrosis in Cardiac Fibroblasts
Yunzi Ma , Zhongbao Yue , Boyu Zhang , Min Yang , Haiyan Lao , Weihua Lai , Yingtong Zeng , Shaorui Chen , Peiqing Liu
PDF
326-339
Cytotoxicity of Structurally Diverse Anthranoids and Correlation with Mechanism of Action and Side Effects
Daniel Pecoraro Demarque , Rui Milton Patrício Silva , Leandro Figueiredo Santos , Andréia Machado Leopoldino , Enilza Maria Espreafico , Norberto Peporine Lopes
PDF
347-353
Design and Evaluation of Gemini Surfactant-Based Lipoplexes Modified with Cell-Binding Peptide for Targeted Gene Therapy in Melanoma Model
Waleed Mohammed-Saeid , Rania Soudy , Richa Tikoo , Kamaljit Kaur , Ronald E Verrall , Ildiko Badea
PDF
363-375
Nano-sized Droplets of Self-Emulsifying System for Enhancing Oral Bioavailability of Chemotherapeutic Agent VP-16 in Rats: A Nano Lipid Carrier for BCS Class IV Drugs
Nayab Khalid , Muhammad Sarfraz , Mosab Arafat , Muhammad Akhtar , Raimar Löbenberg , Nisar Ur Rehman
PDF
398-408
Revisiting FDA’s 1995 Guidance on Bioequivalence Establishment of Topical Dermatologic Corticosteroids: New Research Based Recommendations
Deniz Ozdin , Naveen Sharma , Jorge Lujan-Zilbermann , Philippe Colucci , Isadore Kanfer , Murray P. Ducharme
PDF
413-428
Resveratrol Limits Lipogenesis and Enhance Mitochondrial Activity in HepG2 Cells
Magdalena Izdebska , Mariola Herbet , Monika Gawrońska-Grzywacz , Iwona Piątkowska-Chmiel , Agnieszka Korga , Marcin Sysa , Magdalena Iwan , Dorota Natorska-Chomicka , Ewa Poleszak , Andrzej Wróbel , Sławomir Mandziuk , Jarosław Dudka
PDF
504-515

Clinical Pharmacology and Therapeutics

Polymorphisms of Catechol-O-Methyl Transferase (COMT) Gene in Vulnerability to Levodopa-Induced Dyskinesia
Svetlana A. Ivanova , Valentina M. Alifirova , Ivan V. Pozhidaev , Maxim B. Freidin , Irina A. Zhukova , Diana Z. Osmanova , Natalia G. Zhukova , Yulia A. Mironova , Vladimir V. Tiguntsev , Olga Yu. Fedorenko , Nikolay A. Bokhan , Bob Wilffert , Anton J.M. Loonen
PDF
340-346
Pharmacokinetic Variability in Pediatrics and Intensive Care: Toward a Personalized Dosing Approach
Amélie Marsot
PDF
354-362

Review Articles

The Controversies, Challenges and Complexities of Lyme Disease: A Narrative Review
Marie Claire Van Hout
PDF
429-436
Progress on Active Analgesic Components and Mechanisms of Commonly Used Traditional Chinese Medicines: A Comprehensive Review
Ruizhou Wang , Lu Han , Qixia Gao , Dan Chen , Yun Wang , Xia Zhang , Xin Yu , Yueming Zhang , Zhiyong Li , Changcai Bai
PDF
437-480
Non-alcoholic Steatohepatitis (NASH) Drug Discovery – Building a Consensus on ADME Screening Tools and Clinical Pharmacology Strategies to Aid Candidate Development
Ranjeet Prasad Dash , R. Jayachandra Babu , Nuggehally R Srinivas
PDF
481-495
The Use of High Sensitivity C-Reactive Protein in Cardiovascular Disease Detection
Ana Rita Castro , Sara Oliveira Silva , Sandra Clara Soares
PDF
496-503

Systematic Review and Meta-Analysis

Research on the Scientific Evolution of the Flavonoid Agathisflavone
Vanessa Cristina Meira de Amorim , Markley Silva Oliveira Júnior , Eduardo Muniz Santana Bastos , Victor Diogenes Amaral da Silva , Silvia Lima Costa
PDF
376-385
Rh-endostatin Concomitant with Chemotherapy Versus Single Agent Chemotherapy for Treating Soft Tissue and Bone Sarcomas: A Systematic Review and Meta-Analysis
Zhuo Ma , Lifang Guo , Xiangli Cui , He Liu , Lihong Liu
PDF
386-397