Vol. 21 (2018): Pages 305 - 515 | Journal of Pharmacy & Pharmaceutical Sciences

Pharmaceutical Sciences; Original Research Articles

in vitro- and in vivo Evaluation of Methotrexate-Loaded Hydrogel Nanoparticles Intended to Treat Primary CNS Lymphoma via Intranasal Administration

Leila Pourtalebi Jahromi, Soliman Mohammadi-Samani, Reza Heidari, Amir Azadi

305-317
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Icariside II Attenuates Chronic Hydrocephalus in an Experimental Subarachnoid Hemorrhage Rat Model

Ce Dong, Xing Ming, Zhanying Ye, Pengfei Wang, Lin Wang, Zheng Li, Baogen Pan

318-325
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Calcium Signal Pathway is Involved in Prostaglandin E2 Induced Cardiac Fibrosis in Cardiac Fibroblasts

Yunzi Ma, Zhongbao Yue, Boyu Zhang, Min Yang, Haiyan Lao, Weihua Lai, Yingtong Zeng, Shaorui Chen, Peiqing Liu

326-339
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Cytotoxicity of Structurally Diverse Anthranoids and Correlation with Mechanism of Action and Side Effects

Daniel Pecoraro Demarque, Rui Milton Patrício Silva, Leandro Figueiredo Santos, Andréia Machado Leopoldino, Enilza Maria Espreafico, Norberto Peporine Lopes

347-353
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Design and Evaluation of Gemini Surfactant-Based Lipoplexes Modified with Cell-Binding Peptide for Targeted Gene Therapy in Melanoma Model

Waleed Mohammed-Saeid, Rania Soudy, Richa Tikoo, Kamaljit Kaur, Ronald E Verrall, Ildiko Badea

363-375
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Nano-sized Droplets of Self-Emulsifying System for Enhancing Oral Bioavailability of Chemotherapeutic Agent VP-16 in Rats: A Nano Lipid Carrier for BCS Class IV Drugs

Nayab Khalid, Muhammad Sarfraz, Mosab Arafat, Muhammad Akhtar, Raimar Löbenberg, Nisar Ur Rehman

398-408
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Revisiting FDA’s 1995 Guidance on Bioequivalence Establishment of Topical Dermatologic Corticosteroids: New Research Based Recommendations

Deniz Ozdin, Naveen Sharma, Jorge Lujan-Zilbermann, Philippe Colucci, Isadore Kanfer, Murray P. Ducharme

413-428
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Resveratrol Limits Lipogenesis and Enhance Mitochondrial Activity in HepG2 Cells

Magdalena Izdebska, Mariola Herbet, Monika Gawrońska-Grzywacz, Iwona Piątkowska-Chmiel, Agnieszka Korga, Marcin Sysa, Magdalena Iwan, Dorota Natorska-Chomicka, Ewa Poleszak, Andrzej Wróbel, Sławomir Mandziuk, Jarosław Dudka

504-515
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Clinical Pharmacology and Therapeutics

Polymorphisms of Catechol-O-Methyl Transferase (COMT) Gene in Vulnerability to Levodopa-Induced Dyskinesia

Svetlana A. Ivanova, Valentina M. Alifirova, Ivan V. Pozhidaev, Maxim B. Freidin, Irina A. Zhukova, Diana Z. Osmanova, Natalia G. Zhukova, Yulia A. Mironova, Vladimir V. Tiguntsev, Olga Yu. Fedorenko, Nikolay A. Bokhan, Bob Wilffert, Anton J.M. Loonen

340-346
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Pharmacokinetic Variability in Pediatrics and Intensive Care: Toward a Personalized Dosing Approach

Amélie Marsot

354-362
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Review Articles

The Controversies, Challenges and Complexities of Lyme Disease: A Narrative Review

Marie Claire Van Hout

429-436
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Progress on Active Analgesic Components and Mechanisms of Commonly Used Traditional Chinese Medicines: A Comprehensive Review

Ruizhou Wang, Lu Han, Qixia Gao, Dan Chen, Yun Wang, Xia Zhang, Xin Yu, Yueming Zhang, Zhiyong Li, Changcai Bai

437-480
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Non-alcoholic Steatohepatitis (NASH) Drug Discovery – Building a Consensus on ADME Screening Tools and Clinical Pharmacology Strategies to Aid Candidate Development

Ranjeet Prasad Dash, R. Jayachandra Babu, Nuggehally R Srinivas

481-495
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The Use of High Sensitivity C-Reactive Protein in Cardiovascular Disease Detection

Ana Rita Castro, Sara Oliveira Silva, Sandra Clara Soares

496-503
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Systematic Review and Meta-Analysis

Research on the Scientific Evolution of the Flavonoid Agathisflavone

Vanessa Cristina Meira de Amorim, Markley Silva Oliveira Júnior, Eduardo Muniz Santana Bastos, Victor Diogenes Amaral da Silva, Silvia Lima Costa

376-385
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Rh-endostatin Concomitant with Chemotherapy Versus Single Agent Chemotherapy for Treating Soft Tissue and Bone Sarcomas: A Systematic Review and Meta-Analysis

Zhuo Ma, Lifang Guo, Xiangli Cui, He Liu, Lihong Liu

386-397
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