Vol 18, No 4 (2015)

Table of Contents

Special Issue - Chief Guest Editor: Basil D Roufogalis; Co-Guest Editors: Emanuel Strehler & Srinivas Nammi

Natural Products: Biochemical-Chemical Characterization, and Evidence for Therapeutic Potential
Basil D Roufogalis , Srinivas Nammi , Emanuel E Strehler
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i-ii
Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines
Yu Sato , Takamitsu Sasaki , Shogo Takahashi , Takeshi Kumagai , Kiyoshi Nagata
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316-327
The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes
Paul William Groundwater , Kaiser Hamid , Irene Ng , Vikram J. Tallapragada , David E. Hibbs , Jane Hanrahan
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328-338
Interactions Between Nutraceutical Supplements and Standard Acute Myeloid Leukemia Chemotherapeutics
Paul Spagnuolo
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339-343
Lipid-lowering Activity of Natural and Semi-Synthetic Sterols and Stanols
Dhiaa A Taha , Ellen K Wasan , Kishor M Wasan , Pavel Gershkovich
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344-367
Pre-Clinical Pharmacokinetic and Pharmacodynamic Characterization of Selected Chiral Flavonoids: Pinocembrin and Pinostrobin
Casey L. Sayre , Samaa Alrushaid , Stephanie E. Martinez , Hope D. Anderson , Neal M. Davies
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368-395
Medicinal use of Sceletium: Characterization of Phytochemical Components of Sceletium Plant Species using HPLC with UV and Electrospray Ionization – Tandem Mass Spectroscopy
Srinivas Patnala , Isadore Kanfer
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414-423
Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells
Antony Kam , Kong M Li , Valentina Razmovski-Naumovski , Srinivas Nammi , Kelvin Chan , Georges E Grau , George Q Li
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424-433
Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis
Abeer Abdelhalim , Nasiara Karim , Mary Chebib , Talal Aburjai , Imran Khan , Graham A.R. Johnston , Jane Hanrahan
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448-459
Phytochemical Comparison of the Water and Ethanol Leaf Extracts of the Cree medicinal plant, Sarracenia purpurea L. (Sarraceniaceae)
Carolina Cieniak , Brendan Walshe-Roussel , Rui Liu , Asim Muhammad , Ammar Saleem , Pierre S Haddad , Alain Cuerrier , Brian C Foster , John T Arnason
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484-493
Calebin A: Analytical Development for Pharmacokinetics Study, Elucidation of Pharmacological Activities and Content Analysis of Natural Health Products
Ana Luísa de P. Oliveira , Stephanie E. Martinez , Kalyanam Nagabushnam , Muhammed Majeed , Samaa Alrushaid , Casey L. Sayre , Neal M. Davies
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494-514
Potential Complementary Therapy for Adverse Drug Reactions to Sulfonamides: Chemoprotection Against Oxidative and Nitrosative Stress by TCM Constituents and Defined Mixtures
Lee Zhang , Dao-feng Chen , Xue Yan Xia , Cindy Yip , Michael John Rieder , John Richard Bend
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528-546
Evaluation by microarray of the potential safety of Sarracenia purpurea L. (Sarraceniaceae) a traditional medicine used by the Cree of Eeyou Istchee
Carolina Cieniak , Charlotte McDonald , John Nash , Asim Muhammad , Alaa Badawi , Pierre S Haddad , Alain Cuerrier , Steffany A.L. Bennett , Brian C Foster , John T Arnason
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562-577
Development and Evaluation of a Topical Anti-Inflammatory Preparation Containing Dodonaea polyandra Extract
Bradley S Simpson , Xianling Luo , Jiping Wang , Yunmei Song , David Claudie , Sanjay Garg , Nicholas Smith , Ross McKinnon , Susan Semple
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578-599
Flavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic
Sabia Maini , Brian M. Fahlman , Ed S. Krol
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600-615
A New Cytotoxic Steroidal Glycoalkaloid from the Methanol Extract of Blumea lacera Leaves
Raushanara Akter , Shaikh J. Uddin , Joe Tiralongo , I. Darren Grice , Evelin Tiralongo
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616-633
Effects of Ginkgo biloba Extract EGb 761, Donepezil and their Combination on Central Cholinergic Function in Aged Rats
Christoph Stein , Julia Hopfeld , Helene Lau , Jochen Klein
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634-646
Attenuation of Oxidative Stress in HEK 293 Cells by the TCM Constituents Schisanhenol, Baicalein, Resveratrol or Crocetin and Two Defined Mixtures
John Richard Bend , Xue Yan (Iris) Xue Yan Xia , Daofeng Chen , Abudi Awaysheh , Andrea Lo , Michael John Rieder , Rebecca Jane Rylett
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661-682
Pharmacologic Activities¬ of 3’-Hydroxypterostilbene: Cytotoxic, Anti-Oxidant, Anti-Adipogenic, Anti-Inflammatory, Histone Deacetylase and Sirtuin 1 Inhibitory Activity
Jody K Takemoto , Connie M. Remsberg , Neal M. Davies
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713-727
Selective Induction of Apoptosis by Azadarichta indica Leaf Extract by Targeting Oxidative Vulnerabilities in Human Cancer Cells
Alessia Roma , Pamela Ovadje , Matthew Steckle , Leah Nicoletti , Ammar Saleem , Siyaram Pandey
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729-746
Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components
Emma M. Rath , Anthony P. Duff , Anders P. Håkansson , Catherine S. Vacher , Guo Jun Liu , Robert B. Knott , William Bret Church
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773-824
Hepatotoxicity of Pyrrolizidine Alkaloids
Manuela G Neuman , Lawrence Cohen , Mihai Opris , Radu M Nanau , Hyunjin Jeong
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825-843