Vol. 18 No. 4 (2015)

CLOSED. Special Issue - Chief Guest Editor: Basil D Roufogalis; Co-Guest Editors: Emanuel Strehler & Srinivas Nammi

• Natural Products: Biochemical-Chemical Characterization, and Evidence for Therapeutic Potential

  Basil D Roufogalis, Srinivas Nammi, Emanuel E Strehler

  i-ii

  • PDF
• Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines

  Yu Sato, Takamitsu Sasaki, Shogo Takahashi, Takeshi Kumagai, Kiyoshi Nagata

  316-327

  • PDF
• The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes

  Paul William Groundwater, Kaiser Hamid, Irene Ng, Vikram J. Tallapragada, David E. Hibbs, Jane Hanrahan

  328-338

  • PDF
• Interactions Between Nutraceutical Supplements and Standard Acute Myeloid Leukemia Chemotherapeutics

  Paul Spagnuolo

  339-343

  • PDF
• Lipid-lowering Activity of Natural and Semi-Synthetic Sterols and Stanols

  Dhiaa A Taha, Ellen K Wasan, Kishor M Wasan, Pavel Gershkovich

  344-367

  • PDF
• Pre-Clinical Pharmacokinetic and Pharmacodynamic Characterization of Selected Chiral Flavonoids: Pinocembrin and Pinostrobin

  Casey L. Sayre, Samaa Alrushaid, Stephanie E. Martinez, Hope D. Anderson, Neal M. Davies

  368-395

  • PDF
• Medicinal use of Sceletium: Characterization of Phytochemical Components of Sceletium Plant Species using HPLC with UV and Electrospray Ionization – Tandem Mass Spectroscopy

  Srinivas Patnala, Isadore Kanfer

  414-423

  • PDF
• Curcumin Reduces Tumour Necrosis Factor-Enhanced Annexin V-Positive Microparticle Release in Human Vascular Endothelial Cells

  Antony Kam, Kong M Li, Valentina Razmovski-Naumovski, Srinivas Nammi, Kelvin Chan, Georges E Grau, George Q Li

  424-433

  • PDF
• Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis

  Abeer Abdelhalim, Nasiara Karim, Mary Chebib, Talal Aburjai, Imran Khan, Graham A.R. Johnston, Jane Hanrahan

  448-459

  • PDF
• Phytochemical Comparison of the Water and Ethanol Leaf Extracts of the Cree medicinal plant, Sarracenia purpurea L. (Sarraceniaceae)

  Carolina Cieniak, Brendan Walshe-Roussel, Rui Liu, Asim Muhammad, Ammar Saleem, Pierre S Haddad, Alain Cuerrier, Brian C Foster, John T Arnason

  484-493

  • PDF
• Calebin A: Analytical Development for Pharmacokinetics Study, Elucidation of Pharmacological Activities and Content Analysis of Natural Health Products

  Ana Luísa de P. Oliveira, Stephanie E. Martinez, Kalyanam Nagabushnam, Muhammed Majeed, Samaa Alrushaid, Casey L. Sayre, Neal M. Davies

  494-514

  • PDF
• Potential Complementary Therapy for Adverse Drug Reactions to Sulfonamides: Chemoprotection Against Oxidative and Nitrosative Stress by TCM Constituents and Defined Mixtures

  Lee Zhang, Dao-feng Chen, Xue Yan Xia, Cindy Yip, Michael John Rieder, John Richard Bend

  528-546

  • PDF
• Evaluation by microarray of the potential safety of Sarracenia purpurea L. (Sarraceniaceae) a traditional medicine used by the Cree of Eeyou Istchee

  Carolina Cieniak, Charlotte McDonald, John Nash, Asim Muhammad, Alaa Badawi, Pierre S Haddad, Alain Cuerrier, Steffany A.L. Bennett, Brian C Foster, John T Arnason

  562-577

  • PDF
• Development and Evaluation of a Topical Anti-Inflammatory Preparation Containing Dodonaea polyandra Extract

  Bradley S Simpson, Xianling Luo, Jiping Wang, Yunmei Song, David Claudie, Sanjay Garg, Nicholas Smith, Ross McKinnon, Susan Semple

  578-599

  • PDF
• Flavonols Protect Against UV Radiation-Induced Thymine Dimer Formation in an Artificial Skin Mimic

  Sabia Maini, Brian M. Fahlman, Ed S. Krol

  600-615

  • PDF
• A New Cytotoxic Steroidal Glycoalkaloid from the Methanol Extract of Blumea lacera Leaves

  Raushanara Akter, Shaikh J. Uddin, Joe Tiralongo, I. Darren Grice, Evelin Tiralongo

  616-633

  • PDF
• Effects of Ginkgo biloba Extract EGb 761, Donepezil and their Combination on Central Cholinergic Function in Aged Rats

  Christoph Stein, Julia Hopfeld, Helene Lau, Jochen Klein

  634-646

  • PDF
• Attenuation of Oxidative Stress in HEK 293 Cells by the TCM Constituents Schisanhenol, Baicalein, Resveratrol or Crocetin and Two Defined Mixtures

  John Richard Bend, Xue Yan (Iris) Xue Yan Xia, Daofeng Chen, Abudi Awaysheh, Andrea Lo, Michael John Rieder, Rebecca Jane Rylett

  661-682

  • PDF
• Pharmacologic Activities¬ of 3’-Hydroxypterostilbene: Cytotoxic, Anti-Oxidant, Anti-Adipogenic, Anti-Inflammatory, Histone Deacetylase and Sirtuin 1 Inhibitory Activity

  Jody K Takemoto, Connie M. Remsberg, Neal M. Davies

  713-727

  • PDF
• Selective Induction of Apoptosis by Azadarichta indica Leaf Extract by Targeting Oxidative Vulnerabilities in Human Cancer Cells

  Alessia Roma, Pamela Ovadje, Matthew Steckle, Leah Nicoletti, Ammar Saleem, Siyaram Pandey

  729-746

  • PDF
• Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components

  Emma M. Rath, Anthony P. Duff, Anders P. Håkansson, Catherine S. Vacher, Guo Jun Liu, Robert B. Knott, William Bret Church

  773-824

  • PDF
• Hepatotoxicity of Pyrrolizidine Alkaloids

  Manuela G Neuman, Lawrence Cohen, Mihai Opris, Radu M Nanau, Hyunjin Jeong

  825-843

  • PDF